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Install the Guest Introspection service on VMware ESXi

To protect your VMs with Deep Security Virtual Appliance for file-based protection such as anti-malware, you must install the Guest Introspection service on your ESXi servers.

In vSphere Web Client, go to Home > Networking & Security > Installation, then click the Service Deployments tab.
Click the green plus icon ().

The Deploy Network & Security Services window should appear.
Select Guest Introspection, then click Next.
Select the cluster that contains the ESXi servers and VMs that you want to protect, then click Next.
Select the datastore, the distributed port group used by your NSX cluster, and IP assignment method, , then click Next.
Review your settings, then click Finish.

vSphere may take a few minutes to install the guest introspection service on your ESXi servers. When it is finished, Installation Status will display "Succeeded". To update the status, you may need to refresh the vSphere Web Client.